NCT05108285

Dark Halo and MNV: a Study Between ICGA and OCTA

Dark Halo a New Biomarker in Macular Neovascularization: a Comparative Study Between ICGA and OCTA

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 50 (actual)
• Sponsor: Federico II University · Academic / Other
• Sex: All
• Age: 55 Years – 85 Years
• Healthy volunteers: Not accepted

Summary

The aim of study is to compare the evaluation of dark halo area of macular neovascularization (MNV) between indocyanine green angiography (ICGA) and optical coherence tomography angiography (OCTA) in order to identify OCTA as effective and useful biomarker in MNV

Detailed description

Dark halo is defined as a dark perilesional of flow decrease due to an area of reduced choroidal flow adjacent to the macular neovascularization (MNV). The detection of MNV vascular details was only possible through invasive dye injection, such as fluorescein angiography (FA) or indocyanine green angiography (ICGA). Optical coherence tomography angiography (OCTA) is a recent imaging technique that is able to detect the perfusion and non-perfusion areas carefully. The aim of study is to compare the evaluation of dark halo area of MNV between ICGA and OCTA

Conditions

• Macular Neovascularisation

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Optical Coherence Tomography Angiography (OCTA) and indocyanine green angiography (ICGA)	OCTA and ICGA is able to detect the dark halo as a area of reduced perfusion around MVN

Timeline

• Start date: 2018-01-01
• Primary completion: 2020-12-01
• Completion: 2020-12-15
• First posted: 2021-11-04
• Last updated: 2021-11-17

Locations

1 site across 1 country: Italy