NCT05106179

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma

The Efficacy and Safety of Beta-blockers Drugs in Adults With Spinal Hemangioma: a Prospective Cohort Study

• Status: Unknown
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 1,000 (estimated)
• Sponsor: Center for Vascular Pathology, Moscow · Academic / Other
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Not accepted

Summary

Spinal hemangioma is one of the most common benign vertebral tumours. Being mostly asymptomatic, it is still associated with a pain syndrome especially if encroaches into the neural canal. This study is organised to evaluate the efficacy and safety of β-blockers drugs in adults with spinal hemangioma.

Conditions

• Spinal Tumor
• Spinal Hemangioma
• Beta Blocker Toxicity

Interventions

Type	Name	Description
DRUG	Atenolol Pill	Atenolol is a second-generation hydrophilic β-1-selective adrenergic antagonist, which is primarily metabolised by the kidneys.
DRUG	Propranolol Pill	Propranolol is highly lipophilic, nonselective β-blockers, which is primarily metabolised by the liver.

Timeline

• Start date: 2021-12-01
• Primary completion: 2022-12-01
• Completion: 2023-12-01
• First posted: 2021-11-03
• Last updated: 2021-11-03

Locations

1 site across 1 country: Russia