Trials / Unknown
UnknownNCT05105529
Adaptation to Ozone in Individuals With Asthma/Exercise-induced Bronchoconstriction
Pulmonary and Vascular Adaptations to a 5-days Exercise Protocol in Ozone in Physically Active Individuals With Asthma and Exercise-induced Bronchoconstriction
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- University of British Columbia · Academic / Other
- Sex
- All
- Age
- 18 Years – 50 Years
- Healthy volunteers
- Not accepted
Summary
Researchers found that impairments in the cardiopulmonary system caused by acute exposure to ozone were outweighed by repeated exposures to ozone. The goal of this study is to confirm there will be an adaptation similar to what was previously proved but in individuals with asthma and exercise-induced bronchoconstriction (EIB). The purpose is to examine adaptive responses in a randomized cross-over trial in which physically active individuals will perform submaximal exercise on five days in ozone and filtered air exposures separated by a washout period.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BEHAVIORAL | Exercise | Cycling at 60% of VO2max on a cycle ergometer for 30 minutes |
| OTHER | Ozone | Breathing 170ppb ozone |
| OTHER | Filtere Air | Breathing filtered air |
Timeline
- Start date
- 2021-01-01
- Primary completion
- 2023-01-01
- Completion
- 2023-02-01
- First posted
- 2021-11-03
- Last updated
- 2022-06-02
Locations
2 sites across 1 country: Canada
Source: ClinicalTrials.gov record NCT05105529. Inclusion in this directory is not an endorsement.