Clinical Trials Directory

Trials / Completed

CompletedNCT05103995

Impact of Donor-recipient ABO Matching on Haploidentical Stem Cell Transplantation

Impact of Donor-recipient ABO Matching on Patients' Outcome After Peripheral Blood Stem Cell Haploidentical Stem Cell Transplantation

Status
Completed
Phase
Study type
Observational
Enrollment
510 (actual)
Sponsor
First Affiliated Hospital of Zhejiang University · Academic / Other
Sex
All
Age
15 Years – 70 Years
Healthy volunteers
Not accepted

Summary

the impact of donor-recipient ABO matching on outcome of peripheral blood stem cell haploidentical hematopoietic stem cell transplantation

Detailed description

The impact of donor-recipient ABO compatibility on transplant outcomes had been evaluated in different transplant settings, but had shown different results. The investigators set out to investigate the impact of ABO incompatibility on post-transplant outcomes, engraftment kinetics and blood product requirements, transfusion independence, the incidence of poor graft function (PGF) in anti-T-lymphocyte globulin (ATG) based haplo-SCT with PBSC grafts.

Conditions

Interventions

TypeNameDescription
OTHERno interventionno intervention, just observation

Timeline

Start date
2013-01-01
Primary completion
2019-03-31
Completion
2021-10-01
First posted
2021-11-02
Last updated
2021-11-02

Locations

2 sites across 1 country: China

Source: ClinicalTrials.gov record NCT05103995. Inclusion in this directory is not an endorsement.