NCT05103644

Study of the Therapeutic Effect of Atorvastatin on the Clinical Outcomes in HER2 Negative Breast Cancer Patients"

• Status: Unknown
• Phase: Phase 2 / Phase 3
• Study type: Interventional
• Enrollment: 60 (estimated)
• Sponsor: Beni-Suef University · Academic / Other
• Sex: Female
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Statins, a major class of drugs for treatment of hypercholesterolemia, are widely used due to a notable prevention of cardiovascular disease, and accumulating evidence proposes a promising role of statins in breast cancer

Detailed description

Statin has lipid independent effects include inhibition of inflammatory responses, immunomodulatory actions, apoptotic and antiproliferative effects, which might contribute to the suggested anti-tumoral effects of these agents. The epidemiological evidence projecting statins as anticancer agents is variable, depending on the particular type of cancer in question as well as the class of statin used

Conditions

• Breast Cancer

Interventions

Type	Name	Description
DRUG	Atorvastatin 80mg	patients received statin experimental group
OTHER	placebo	patients received placebo control group

Timeline

• Start date: 2021-10-30
• Primary completion: 2023-12-30
• Completion: 2024-12-30
• First posted: 2021-11-02
• Last updated: 2022-11-02

Locations

2 sites across 1 country: Egypt