NCT05102825

Imaging Measures of Respiratory Health Registry

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 1,000 (estimated)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 0 Years – 99 Years
• Healthy volunteers: Accepted

Summary

This is a prospective, observational cohort registry that aims to collect data on pulmonary structure and function in healthy people and those with respiratory disease, using structural and functional pulmonary 1H-MRI and hyperpolarized 129Xe-MRI. Outcome measures generated from MRI may include but are not limited to measures of regional ventilation, pulmonary microarchitecture, and regional gas exchange. Additionally, one of the goals of the registry is to facilitate the development of novel image analysis techniques that have not yet been invented. These data will be stored along with demographic data, clinical data, and pulmonary function testing (PFT) data. This is an open registry. Eligible local and international investigators/institutions can apply for access.

Conditions

• Respiratory Disease
• Healthy

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	1H and Xe-129 MRI	Traditional 1H-MRI (room air inhalation) and Xe-129 MRI (requires inhalation of Xenon 129 gas).

Timeline

• Start date: 2020-06-11
• Primary completion: 2045-06-01
• Completion: 2045-06-01
• First posted: 2021-11-02
• Last updated: 2021-11-02

Locations

2 sites across 1 country: Canada