NCT05100355

Management of the Lack of Blood Return on a Central Venous Catheter (CVC) Before Chemotherapy

Management of the Lack of Blood Return on a Central Venous Catheter (CVC) Before Chemotherapy in a Day Unit: Phase III Randomised Multicentre Study

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 92 (actual)
• Sponsor: Institut Cancerologie de l'Ouest · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Compare two methods of managing the lack of CVC blood return : opacification using contrast media injection or radio-clinical method with a simple chest X-ray followed by a rapid infusion of physiological serum

Detailed description

The use of CVC is part of daily life in onco-hematology, particularly for chemotherapy treatments in the Day Unit (DU). Among the possible complications and dysfunctions, the most frequent is the lack of CVC blood return, which can be responsible for a disorganization of the patient's management in the Day Unit (delay in patient management). In this study, the 2 most commonly used schemes are compared in a randomised multicentre study. The first scheme is a radiological circuit with opacification using contrast media injection. The second scheme is radio-clinical with a chest X-ray to check the correct functioning of the CVC followed by a rapid infusion of physiological serum. The patient management is compared for the two schemes in term of delay (delay from start to end time of patient management). The safety and the cost of both schemes is compared.

Conditions

• Catheter Dysfunction

Interventions

Type	Name	Description
PROCEDURE	Physiological serum injection	In case of lack of CVC blood return, Physiological serum is injected in the CVC after Chest X-Ray
PROCEDURE	Contrast agent injection	In case of lack of CVC blood return, Contrast agent is injected in the CVC after Chest X-Ray

Timeline

• Start date: 2022-03-09
• Primary completion: 2025-02-26
• Completion: 2025-06-26
• First posted: 2021-10-29
• Last updated: 2025-12-02

Locations

9 sites across 1 country: France