Trials / Completed
CompletedNCT05100043
Interleukin 4 and Interferon Gamma Predictors of Human Papillomavirus Immunotherapy in Warts
IL-4 and IFN-γ As Immunologic Predictors of Response to HPV Immunotherapy in Warts
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 80 (actual)
- Sponsor
- Zagazig University · Other Government
- Sex
- All
- Age
- 36 Months
- Healthy volunteers
- Not accepted
Summary
In the present study the investigators assessed the invitro role of IL-4 and IFN-γ in predicting the response to bivalent HPV vaccine after whole blood stimulation
Detailed description
40 Patients and 40 controls are enrolled in the study. Participants suffer from chronic recurrent cutaneous and genital warts. Blood samples were withdrawn then whole blood cultures are prepared. Cultures are stimulated with bivalent HPVvaccine. IL-4 and IFN-γ measurement in culture supernatants by ELISA. IL-4 and IFN-γ are investigated to predict the therapeutic response to bivalent HPV vaccine immunotherapy in warts.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| BIOLOGICAL | IL-4 and IFN-γ measurements | Blood samples are withdrawn from participants and whole blood cultures are prepared and stimulated by bivalent HPV vaccine.IL-4 and IFN-γ are measured in culture supernatants |
Timeline
- Start date
- 2020-01-03
- Primary completion
- 2020-07-03
- Completion
- 2021-03-02
- First posted
- 2021-10-29
- Last updated
- 2025-02-19
Locations
1 site across 1 country: Egypt
Source: ClinicalTrials.gov record NCT05100043. Inclusion in this directory is not an endorsement.