NCT05098899

MyGeneMyDiet Trial for Weight Management

Interventions Using Genomics-based Strategies (InGeSt) Towards Enhanced Nutrition Recommendations: A Proof-of-concept RCT for the DNA-based Nutrition and Lifestyle Recommendations in Overweight and Obese Filipino Adults

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 62 (actual)
• Sponsor: Food and Nutrition Research Institute, Philippines · Other Government
• Sex: All
• Age: 19 Years – 59 Years
• Healthy volunteers: Accepted

Summary

The study aims to determine if genotype-based nutrition and lifestyle advice is effective for the management of overweight and obesity among Filipino adults compared to the usual standard of care.

Detailed description

The primary objective of the study is to determine if providing a nutrition and lifestyle advice with genetic information can promote the attainment of 5-10% weight loss, and improvements on body mass index, waist circumference, and body fat percentage among Filipino adults with overweight and obesity. Additionally, changes in dietary intake, eating behaviour, physical activity level, biochemical parameters (HbA1c and blood lipid profile), motivation for weight loss, and knowledge and perceptions on nutrigenomics and genetic testing will also be assessed.

Conditions

• Overweight and Obesity

Interventions

Type	Name	Description
GENETIC	MyGeneMyDiet® Recommendations for Weight Management	This group will receive Nutrition and Lifestyle recommendation based on SNPs known to have an impact to body weight and body composition, and responses to physical activity and dietary fat intake
OTHER	Usual Standard of Care for Weight Management	This group will receive the conventional and standard nutrition lifestyle recommendation for weight management

Timeline

• Start date: 2021-12-01
• Primary completion: 2024-05-30
• Completion: 2024-08-31
• First posted: 2021-10-28
• Last updated: 2025-03-12

Locations

1 site across 1 country: Philippines