NCT05098015

Randomized Controlled Trial of Game Changers

Controlled Trial of Game Changers: A Group Intervention to Train HIV Clients to be Change Agents for HIV Prevention in Uganda

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 809 (actual)
• Sponsor: RAND · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The study is a randomized controlled trial (RCT) of Game Changers, an 8-session peer-led group intervention that aims to empower and mobilize people living with HIV (PLWH) to be agents for HIV prevention in their social networks.

Detailed description

This RCT of Game Changers, a peer-led group intervention for persons living with HIV (PLWH) in Uganda, will test intervention effects on the primary outcomes of reduced condomless sex, increased HIV testing, and decreased enacted HIV stigma among social network members. We will recruit 210 PLWH, randomizing 105 to the intervention and 105 to an attention control. Each PLWH will be asked to recruit up to 4 social network members to complete assessments (736 total, 368/arm). All participants will complete surveys at baseline and 6-, 12-, and 18-months post-baseline.

Conditions

• HIV Prevention

Interventions

Type	Name	Description
BEHAVIORAL	Game Changers	8-session group intervention that uses didactic instruction, role plays and experience sharing to empower participants to engage in HIV prevention advocacy.

Timeline

• Start date: 2022-01-24
• Primary completion: 2024-10-25
• Completion: 2024-10-25
• First posted: 2021-10-28
• Last updated: 2026-01-15
• Results posted: 2026-01-15

Locations

1 site across 1 country: Uganda