NCT05097781

Local Radiotherapy in Combination With Immunotherapy in Advanced Solid Tumors Patients

Evaluating the Efficacy of Local Radiotherapy in Combination With Immunotherapy in Advanced Solid Tumors: a Phase II Prospective Clinical Study

• Status: Unknown
• Phase: Phase 2
• Study type: Interventional
• Enrollment: 55 (estimated)
• Sponsor: Ruijin Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 75 Years
• Healthy volunteers: Not accepted

Summary

This is a phase II study to observe efficacy of combining local radiotherapy with PD-1blockade in patients with advanced solid tumors. All patients will accept at least one site of radiotherapy together with PD-1 blockade. The study will evaluate changes of unirradiated and irradiated lesions.

Conditions

• Solid Tumor

Interventions

Type	Name	Description
DRUG	PD-1 blocking antibody	All patients with more than one distant metastatic lesions will accept at least one site of radiotherapy and PD-1 blockade at the same time.

Timeline

• Start date: 2021-03-21
• Primary completion: 2023-06-01
• Completion: 2024-09-01
• First posted: 2021-10-28
• Last updated: 2021-10-28

Locations

1 site across 1 country: China