NCT05094193

Trocar-site Infiltration Versus TAP-block

Trocar-site Infiltration With Ropivacaine Versus Tranversus Abdominis Plane Block Following Laparoscopic Cholecystectomy: a Double-blinded, Randomized-controlled Trial

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 100 (estimated)
• Sponsor: Tunis University · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Not accepted

Summary

For symptomatic gall bladder disorders (cholelithiasis and cholecystitis), laparoscopic cholecystectomy (LC) has been considered as the gold standard treatment. However, these minimally invasive technique is associated with acute moderate pain during the 24 hours postoperative, which is routinely managed using opioids. The transversus abdominis plane (TAP) block has been used as part of a multimodal analgesia strategy. Besides, Wang et al found that TAP block is more effective than a conventional pain control, but not significatively different from another local incisional pain control that is port site infiltration.So, the aim of this study, is to compare the analgesic efficacy and safety of trocar-site infiltration with ropivacaine with ultrasound-guided TAP block following laparoscopic cholecystectomy when used as part of multimodal analgesia.

Conditions

• Laparoscopic Cholecystectomy

Interventions

Type	Name	Description
PROCEDURE	Trocar-site infiltration	20 mL of ropivacaine 0.375% (6 mL in 10 mm trocar site and 4 mL in 6 mm trocar site)
PROCEDURE	TAP block	bilateral ultrasound-guided TAP block with 20 mL of ropivacaine 0.375% in each side
PROCEDURE	Trocar site infiltration placebo	20 mL of normal saline
PROCEDURE	TAP block placebo	bilateral ultrasound-guided TAP block with 20 mL of normal saline in each side

Timeline

• Start date: 2021-10-01
• Primary completion: 2021-12-31
• Completion: 2022-01-31
• First posted: 2021-10-26
• Last updated: 2021-10-26

Locations

1 site across 1 country: Tunisia