NCT05092672

Physical Activity, Air Pollution, and High Blood Pressure

Impact of Traffic-related Air Pollution on the Cardiovascular and Pulmonary Response to Physical Activity in Patients With Hypertension

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 21 (actual)
• Sponsor: University of British Columbia · Academic / Other
• Sex: All
• Age: 40 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

The investigators are investigating the effects of traffic-related air pollution (TRAP) on the cardiovascular and pulmonary response to exercise in patients with hypertension using a real world randomized, crossover study design. Participants will be exposed to 2 conditions: a low TRAP environment and a high TRAP environment. Each exposure will consist of 30 min of moderate-intensity exercise. Cardiovascular and pulmonary health outcomes will be measured before, during, and up to 24 hours following exposures. A minimum washout period of 1 week will be used to minimize carryover effects.

Conditions

• Essential Hypertension

Interventions

Type	Name	Description
BEHAVIORAL	Exercise	Participants will engage in moderate-intensity (40-59% HRR) exercise for 30 min

Timeline

• Start date: 2021-11-15
• Primary completion: 2024-08-01
• Completion: 2024-08-01
• First posted: 2021-10-25
• Last updated: 2024-08-12

Locations

1 site across 1 country: Canada