NCT05091255

Cryotherapy in the Treatment of Desmoid Tumors

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 94 (estimated)
• Sponsor: Istituto Ortopedico Rizzoli · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

Desmoid tumor is a benign neoplasm with an unpredictable course and a high rate of local recurrence if treated surgically. Therefore, over time the surgical approach has become conservative, preferring simple observation or medical therapy in case of disease progression through the use of hormonal therapy and low-dose chemotherapy. Since this neoplasm remains benign, our study aims to avoid chemotherapy in patients usually young through the use of a minimally invasive treatment such as cryotherapy.

Conditions

• Desmoid

Interventions

Type	Name	Description
PROCEDURE	Cryotherapy	The procedure involves general or peripheral anesthesia and percutaneous treatment under CT control with probes capable of forming ice spheres of up to 3 cm that will be used in sufficient number to treat the neoplasm completely.

Timeline

• Start date: 2021-05-20
• Primary completion: 2027-01-01
• Completion: 2027-01-01
• First posted: 2021-10-25
• Last updated: 2025-08-01

Locations

1 site across 1 country: Italy