Trials / Unknown
UnknownNCT05090137
Quantifying Congestion by Ultrasound
Quantifying Interstitial and Intravascular Fluid Accumulation by Ultrasound Following Temporary Suspension of Loop Diuretics in Patients With Heart Failure
- Status
- Unknown
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 20 (estimated)
- Sponsor
- NHS Greater Glasgow and Clyde · Academic / Other
- Sex
- All
- Age
- 19 Years – 100 Years
- Healthy volunteers
- Not accepted
Summary
The investigators will determine the feasibility of identifying and quantifying changes in interstitial and intravascular congestion by imaging in participants with heart failure. The investigators will either continue or temporarily suspend both loop diuretics and mineralo-corticoid antagonists (MRA) for 48 hours in participants with heart failure that is both stable and mild and compare measurements of interstitial (B-lines) and intra-vascular fluids (IVC and JV diameter and renal venous flow) by ultrasound and, in a subset of participants without contra-indications, by cardiac MRI.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Diuretics | As per group descriptions |
Timeline
- Start date
- 2021-11-01
- Primary completion
- 2022-12-01
- Completion
- 2022-12-01
- First posted
- 2021-10-22
- Last updated
- 2021-10-22
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT05090137. Inclusion in this directory is not an endorsement.