NCT05088486

The Role of Genetic Factors in the Development of Arterial Hypertension in the Kazakh Population

Preventive and Personalized Medicine (2021-2023)

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 1,200 (actual)
• Sponsor: Asfendiyarov Kazakh National Medical University · Academic / Other
• Sex: All
• Age: 18 Years – 55 Years
• Healthy volunteers: —

Summary

This is a GWAS study that aims to identify possible candidate genes associate to arterial hypertension by exploring single nucleotide polymorphism (SNP) in a group of arterial hypertension, in the Kazakh population. The investigators hypothesize that the careful phenotyping of the subject sand matching with increase the power to find SNP significantly associate with arterial hypertension

Detailed description

A genome-wide association study (GWAS) is an approach used in genetics research to associate specific genetic variations with particular diseases. The method involves scanning the genomes from many different people and looking for genetic markers that can be used to predict the presence of a disease. Once such genetic markers are identified, they can be used to understand how genes contribute to the disease and develop better prevention and treatment strategies.

Conditions

• Arterial Hypertension

Interventions

Type	Name	Description
GENETIC	DNA analysis	GWAS

Timeline

• Start date: 2022-03-30
• Primary completion: 2023-01-20
• Completion: 2023-01-20
• First posted: 2021-10-22
• Last updated: 2023-03-14

Locations

1 site across 1 country: Kazakhstan