NCT05086133

cTBS on First-episode Drug Naive Patients With Schizophrenia

The Effect of cTBS on First-episode Drug Naive Patients With Schizophrenia

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 44 (actual)
• Sponsor: Central South University · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

cTBS is a promising novel intervention, which have strong potentials on moderating disease syndrome, suck as verbal hallucination, and cognitive deficits in schizophrenia, as it has been proved for the treatment of depression. Therefore, the investigators designed this randomized controlled clinical trial to evaluate the efficacy and safety of cTBS on prevention and treatment for cognitive deficiency, psychotic syndrome and metabolic side-effects in drug-naive first episode individual with schizophrenia.

Detailed description

cTBS is a promising novel intervention, which have strong potentials on moderating disease syndrome, suck as verbal hallucination, and cognitive deficits in schizophrenia, as it has been proved for the treatment of depression. Therefore, the investigators designed this randomized controlled clinical trial to evaluate the efficacy and safety of cTBS on prevention and treatment for cognitive deficiency, psychotic syndrome and metabolic side-effects in drug-naive first episode individual with schizophrenia.

Conditions

• Schizophrenia

Interventions

Type	Name	Description
DEVICE	transcranial magnetic stimulation	transcranial magnetic stimulation with continuous theta burst pattern, 90% RMT, 50Hz within train and 5Hz train for 200 train and 40 second in total.
DEVICE	sham stimulation	TMS coil vertical to the brain surface, with same protocol as cTBS

Timeline

• Start date: 2021-11-20
• Primary completion: 2022-11-15
• Completion: 2023-06-01
• First posted: 2021-10-20
• Last updated: 2022-11-17

Locations

1 site across 1 country: China