NCT05084599

Effect of 90% Effective Dose of Metaraminol in Supine and Left Tilt Positions on Cesarean Section

Effect of 90% Effective Dose of Metaraminol in Supine and Left Tilt Positions on Cesarean Section：A Non-inferiority Trial

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 124 (actual)
• Sponsor: Peking University People's Hospital · Academic / Other
• Sex: Female
• Age: 18 Years – 40 Years
• Healthy volunteers: Not accepted

Summary

For hypotension after spinal anesthesia, metaraminol has different 90% effective doses in the supine position and the left-tilt position. We plan to conduct a non-inferiority trial to compare the effects of the two on the fetus and the mother.

Conditions

• Cesarean Section Complications

Interventions

Type	Name	Description
DRUG	Metaraminol 2.7μg/kg/min	After spinal anesthesia, the patient was placed in a supine position until the fetus was delivered, and metaraminol was given at an initial rate of 2.7μg/kg/min throughout the process.
DRUG	Metaraminol 2μg/kg/min	After spinal anesthesia, the patient was placed in left-tilt position until the fetus was delivered, and metaraminol was given at an initial rate of 2μg/kg/min throughout the process.

Timeline

• Start date: 2022-05-12
• Primary completion: 2024-01-31
• Completion: 2024-01-31
• First posted: 2021-10-20
• Last updated: 2024-02-01

Locations

1 site across 1 country: China