Clinical Trials Directory

Trials / Completed

CompletedNCT05083585

A Study Evaluating the Immunogenicity of Different Clinical Trial Materials of Ad26.RSV.preF- Based Vaccine in Adults Aged 60 - 75 Years Old

A Randomized, Double-blind Phase 3 Study to Compare the Immunogenicity of Clinical Trial Material of an Ad26.RSV.preF-based Vaccine for Phase 3 With Clinical Trial Material Representative of Phase 2b in Adults Aged 60 to 75 Years

Status
Completed
Phase
Phase 3
Study type
Interventional
Enrollment
250 (actual)
Sponsor
Janssen Vaccines & Prevention B.V. · Industry
Sex
All
Age
60 Years – 75 Years
Healthy volunteers
Accepted

Summary

The purpose of this study is to demonstrate non-inferiority in terms of humoral immune responses induced by vaccination with one dose of the Phase 3 clinical trial material (CTM) compared with one dose of the Phase 2b CTM.

Conditions

Interventions

TypeNameDescription
BIOLOGICALAd26.RSV.preF-based vaccineAd26.RSV.preF-based vaccine will be administered as a single intramuscular injection.

Timeline

Start date
2021-10-08
Primary completion
2022-03-07
Completion
2022-09-22
First posted
2021-10-19
Last updated
2025-05-25
Results posted
2023-09-11

Locations

9 sites across 1 country: United States

Regulatory

Source: ClinicalTrials.gov record NCT05083585. Inclusion in this directory is not an endorsement.