NCT05083026

Neutralizing Antibody Level After COVID-19 Vaccination

Neutralizing Antibody Level After COVID-19 Vaccination in Hospital Works.

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 51 (estimated)
• Sponsor: Kyungpook National University Hospital · Academic / Other
• Sex: All
• Age: 20 Years – 60 Years
• Healthy volunteers: —

Summary

1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2. investigate the factors on antibody titer.

Detailed description

1. serial of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 1) semi-quantitative measurement of neutralizing antibody at 2, 4, 6, 9, 12 month after COVID-19 vaccination 2) investigate the duration maintaining acceptable range (over 30% inhibition) 2. investigate the factors on antibody titer at 2 month after vaccination 1) potential factors: age, sex, body weight, height, use of medication, use of antipyretics (NSAID or tyrenol), side effect of COVID-19 vaccination 2) correlation between antibody titer and potential factors 3. Compare 4 diagnostic ELISA kit at 2 month after vaccination 1) measure neutralizung antibody using ELISA kits from 4 different companies 2) investigate correlation coefficient of antibody titer between companies

Conditions

• Covid19

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	COVID-19 neutralizing antibody	This study enrolled persons already who received COVID-19 vaccination under government policy. 1. We collect 5mL blood at 2, 4, 6, 9, 12 months after COVID-19 vaccination 2. isolate serum and store in -80 degree deep freezer 3. measure neutralizing Antibody

Timeline

• Start date: 2021-06-02
• Primary completion: 2024-12-31
• Completion: 2024-12-31
• First posted: 2021-10-19
• Last updated: 2023-10-04

Locations

1 site across 1 country: South Korea