NCT05080166

UPLYFT For Lymphoma Survivors

An Intervention for Fear of Cancer Recurrence for Lymphoma Survivors

• Status: Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 74 (estimated)
• Sponsor: Dana-Farber Cancer Institute · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The main purpose of this study is to field test and pilot an intervention called UPLYFT (Understand and Prevail: Lymphoma Fear of Recurrence Therapy) that includes information about lymphoma survivorship and tools to improve quality of life and reduce lymphoma-related worries among lymphoma survivors.

Detailed description

This is a two phase pilot study to develop and pilot the UPLYFT (Understand and Prevail: Lymphoma Fear of Recurrence Therapy) program intervention that includes lymphoma survivorship information and acceptance and commitment therapy strategies to alleviate fear of cancer recurrence, reduce distress, and improve quality of life among lymphoma survivors. Phase 1 will be a two-part development process of the UPLYFT program based on interview feedback from lymphoma and mental health clinicians and then feedback from a six-person group of lymphoma survivors after participation in an UPLYFT program field test. Phase 2 is a randomized pilot study using the UPLFYT program finalized in Phase 1. Research procedures include: * In depth interview (lymphoma and mental health clinicians) * Screening for eligibility * 6 weekly intervention sessions (lymphoma survivors) * Baseline Assessments and Questionnaires (lymphoma survivors) 74 people are expected to participate in this study with 14 in Phase 1 and 60 in Phase 2. The American Society of Hematology is providing funding for the trial.

Conditions

• Lymphoma
• Survivorship

Interventions

Type	Name	Description
OTHER	Interview with Clinicians	One time, qualitative interview of clinicians for feedback on UPLYFT intervention
OTHER	Field Test of UPLYFT with Lymphoma Survivors	6 session of UPLYFT intervention with Lymphoma Survivors for feedback
BEHAVIORAL	Pilot of UPLYFT with Lymphoma Survivors	6 session of UPLYFT intervention with Lymphoma Survivors

Timeline

• Start date: 2022-02-08
• Primary completion: 2026-05-31
• Completion: 2026-08-31
• First posted: 2021-10-15
• Last updated: 2026-02-24

Locations

1 site across 1 country: United States