NCT05078788

Holmium Laser Uretherotomy in Combination With Intralesional Steroids in Bulbar Uretheral Stricture

Efficacy of Holmium Laser Uretherotomy in Combination With Intralesional Steroids in the Treatment of Bulbar Uretheral Stricture

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 124 (actual)
• Sponsor: Ain Shams University · Academic / Other
• Sex: Male
• Age: 26 Years – 69 Years
• Healthy volunteers: Not accepted

Summary

the purpose is to evaluate the outcome of visual internal uretherotomy with Holmium laser along with intralesional steroid injection.

Detailed description

In this study, the investigator evaluates the efficacy of Holmium laser in combination with intra lesional steroid injection in the treatment of bulbar urethral strictures

Conditions

• Urethral Stricture

Interventions

Type	Name	Description
PROCEDURE	Laser uretherotomy	Holmium YAG Laser with pulse energy from 1-2 Joule, frequency from 10-15 Hertz and total power from 3.0 to 30.0 Watt were set up, respectively, based on the extent of the lesions. Scar tissue was incised at the position of 12-o'clock under the guidance of guidewire or ureteric catheter till fresh mucosa appeared.
PROCEDURE	Laser uretherotomy with triamcinolone	After laser urethrotomy, 80 mg of triamcinolone (diluted with normal saline to 10 ml) will be injected by using an injection needle (5 F size and 23 G needle size) at 10 sites, 1 ml each, along the site of urethrotomy and circumferentially.

Timeline

• Start date: 2020-06-02
• Primary completion: 2021-02-02
• Completion: 2021-09-10
• First posted: 2021-10-15
• Last updated: 2021-10-15

Locations

1 site across 1 country: Egypt