NCT05077605

Effect of Extubation on Respiratory Function

Electrical Impedance Tomography: Effect of Extubation on Functional Residual Capacity

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 34 (actual)
• Sponsor: Centre Hospitalier Intercommunal de Toulon La Seyne sur Mer · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The extubation phase is a risky period of anesthesia management. During this step, serious complications can arise: hypoxemia, laryngospasm, pharyngeal obstruction, pneumonia… In spite of these complications, extubation and its impact on respiratory function, particularly on the Functional Residual Capacity (FRC), remains poorly studied because of the difficulty to make bedside measurements. The PulmoVista 500 is a clinical routine which provide effective non-invasive bedside measurements. It would be interesting to evaluate the impact of extubation on respiratory function, and more specifically FRC changes during and after extubation. This study will allow a better physiopathological knowledge and a quality improvement patient extubation management.

Detailed description

The aim of this study is to evaluate the variation of functional residual capacity and its distribution before and after extubation. Patients with scheduled surgery and receiving general anesthesia with orotracheal intubation are included and the measurements will be performed in the post-interventional monitoring room (PICU). EELI data will be collected before extubation and then at T0, then T5, T10, T15 and T20 minutes. No subsequent follow-up is required.

Conditions

• Functional Residual Capacity

Interventions

Type	Name	Description
OTHER	Functional residual capacity measure by electrical impedance tomography	Patient functional residual capacity will be measured by electrical impedance tomography before extubation and then at 0, 10, 15 and 20 min after extubation.

Timeline

• Start date: 2021-11-05
• Primary completion: 2022-06-30
• Completion: 2022-06-30
• First posted: 2021-10-14
• Last updated: 2026-04-13

Locations

1 site across 1 country: France