NCT05075863

Efficacy of Letrozole Versus Clomiphene Citrate on Ovulation Induction in Patients With Polycystic Ovarian Syndrome

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 78 (actual)
• Sponsor: Nishtar Medical University · Academic / Other
• Sex: Female
• Age: 18 Years – 30 Years
• Healthy volunteers: Accepted

Summary

We aimed this study to determine and compare frequency of induction of ovulation in women with polycystic ovarian syndrome treated with Letrozole versus clomiphene citrate as published literature shows variations.

Detailed description

Discrepancy between ovulation induction rate and pregnancy rate is related to anti-estrogenic effects on cervical mucus and endometrium and long acting gonadotrophins are more effective than clomiphene citrate. This study was aimed at comparing frequency of induction of ovulation in women with polycystic ovarian syndrome treated with Letrozole versus clomiphene citrate.

Conditions

• Polycystic Ovary Syndrome

Interventions

Type	Name	Description
DRUG	Letrozole	Letrozole as 5mg from day 3 to 7 of menstrual cycle

Timeline

• Start date: 2021-01-01
• Primary completion: 2021-06-30
• Completion: 2021-06-30
• First posted: 2021-10-13
• Last updated: 2021-10-14

Locations

1 site across 1 country: Pakistan