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UnknownNCT05072275

Prospective Electronic Polygenic Risk Study

Prospective Electronic Polygenic Risk Study (PEPRS) - First Phase

Status
Unknown
Phase
Study type
Observational
Enrollment
1,000 (estimated)
Sponsor
Scripps Translational Science Institute · Academic / Other
Sex
All
Age
45 Years – 65 Years
Healthy volunteers
Not accepted

Summary

This study will investigate the role of polygenic risk scores (PRS) in preventive health.

Detailed description

This study will investigate the role of polygenic risk scores (PRS) in preventive health. Specifically, the purpose of this study is to determine whether knowledge of the degree of coronary artery disease (CAD) genetic risk, as measured and conveyed by a PRS, influences patient and physician decision-making during short-term (6 month) and long-term (2 year) follow-up. The initial findings of this study will be used to plan an expanded second phase study with the purpose of prospectively validating that these decision-making changes lead to improvements in clinical outcomes.

Conditions

Timeline

Start date
2023-03-01
Primary completion
2023-11-01
Completion
2023-11-01
First posted
2021-10-08
Last updated
2022-11-07

Source: ClinicalTrials.gov record NCT05072275. Inclusion in this directory is not an endorsement.

Prospective Electronic Polygenic Risk Study (NCT05072275) · Clinical Trials Directory