Trials / Recruiting
RecruitingNCT05072262
DSAEK/DMEK and Cystoid Macular Edema - the Role for Topical NSAIDs (Nepafenac) (DMEC)
A Randomized Clinical Two-arm Trial Comparing Inflammation and Cystoid Macular Edema for the Medication Regimens Postoperative Topical NSAIDs and Steroids to Only Postoperative Topical Steroids in Patients Undergoing Corneal Endothelial Transplantations (DMEC)
- Status
- Recruiting
- Phase
- Phase 4
- Study type
- Interventional
- Enrollment
- 300 (estimated)
- Sponsor
- Oslo University Hospital · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The DMEC trial is a randomized clinical two-arm trial comparing inflammation and cystoid macular edema for the medication regimens postoperative topical NSAIDs and steroids to only postoperative topical steroids in patients undergoing corneal endothelial transplantations (DSAEK or DMEK).
Conditions
- Descemet Stripping Automated Endothelial Keratoplasty (DSAEK)
- Descemet Membrane Endothelial Keratoplasty (DMEK)
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Nepafenac Ophthalmic | Topical nepafenac (Nevanac) 3 mg/ml |
| DRUG | Dexamethasone Ophthalmic | Topical dexamethasone 1 mg/ml (Spersadex) |
Timeline
- Start date
- 2022-11-25
- Primary completion
- 2024-06-01
- Completion
- 2026-10-01
- First posted
- 2021-10-08
- Last updated
- 2022-12-01
Locations
1 site across 1 country: Norway
Source: ClinicalTrials.gov record NCT05072262. Inclusion in this directory is not an endorsement.