Trials / Recruiting
RecruitingNCT05071131
Effect of Inulin on Gut Microbiota and Gut Barrier in Chronic Kidney Disease
Investigating the Effect of Inulin on Gut Microbiota and Gut Barrier in Advanced Chronic Kidney Disease - a Randomised, Placebo-controlled Trial
- Status
- Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 40 (estimated)
- Sponsor
- Charite University, Berlin, Germany · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Not accepted
Summary
An adequate fiber intake is crucial for a well-balanced diet and reduces the risk of chronic diseases. However, nutritional recommendations for chronic kidney disease patients lead to an insufficient fiber intake with possible maladaptive effects on the gut microbiome. Therefore, we want to study the effects of a 35-day inulin supplementation on the gut microbiome, gut barrier function, bacterial metabolites and immune cell states in chronic kidney disease patients.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | Inulin | 1 sachet à 15 grams daily for 7 days, followed by 2 sachets à 15 grams daily for 28 days |
| DIETARY_SUPPLEMENT | Placebo | 1 sachet à 15 grams daily for 7 days, followed by 2 sachets à 15 grams daily for 28 days |
Timeline
- Start date
- 2022-02-01
- Primary completion
- 2026-02-01
- Completion
- 2027-02-01
- First posted
- 2021-10-08
- Last updated
- 2024-06-25
Locations
1 site across 1 country: Germany
Source: ClinicalTrials.gov record NCT05071131. Inclusion in this directory is not an endorsement.