NCT05067881

Post-COVID-19 Pneumo-hematocele

Post COVID-19 Pneumo-hematocele: Clinical Presentation and Treatment Pathway

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 37 (actual)
• Sponsor: Hospital General Ajusco Medio · Academic / Other
• Sex: All
• Age: 18 Years – 80 Years
• Healthy volunteers: Not accepted

Summary

Introduction. As the COVID-19 pandemic has continued, an increasing number of long-term complications are emerging. Recently, the appearance of characteristic pulmonary lesions has been noted, being described as post COVID-19 pneumatocele. The aim of this study is to describe the clinical, histopathologic and imaging features of post COVID-19 pneumo-hematoceles (PHC) and secondarily to suggest a treatment algorithm in these patients. Methods. A retrospective study was performed in patients admitted with diagnosis of SARS-CoV2 infection from March 2020 to September 2021 who presented PHC on imaging studies. Clinical and demographic variables were recorded and CT scans were analyzed. A logistic regression analysis was performed to determine the risk for rupture according to PHC characteristics. It appears that PHC occurs secondary to encapsulation of blood accumulation, the result of micro capillary bleeding, with partial reabsorption of blood and subsequent air filling. The recommendation is to operate on patients with PHC of 5cm and those with persistent lesions of 3cm.

Conditions

• COVID-19 Respiratory Infection

Interventions

Type	Name	Description
PROCEDURE	Pulmonary resection	Resection of pneumohematocele

Timeline

• Start date: 2020-03-01
• Primary completion: 2020-03-01
• Completion: 2021-09-20
• First posted: 2021-10-05
• Last updated: 2021-10-05

Locations

1 site across 1 country: Mexico