Trials / Not Yet Recruiting
Not Yet RecruitingNCT05066945
Application of ctDNA in the Evaluation of Curative Effect and Prognosis of SCLC Patients
Application of Circulating Tumor (ctDNA) in the Evaluation of Curative Effect and Prognosis of Small Cell Lung Cancer (SCLC) Patients
- Status
- Not Yet Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 40 (estimated)
- Sponsor
- Xiangya Hospital of Central South University · Academic / Other
- Sex
- All
- Age
- 18 Years – 80 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to evaluate the application value of circulating tumor DNA(ctDNA) with efficacy evaluation and prognostic assessment in patients with unresectable SCLC, who were receiving radiotherapy and chemotherapy treatment.
Detailed description
1. According to each point in time of ctDNA, to analyze the dynamic changes of tumor burden and clonal subtypes which to evaluate the application value of ctDNA in curative efficacy evaluation. 2. Compare the two time points before and after radiotherapy and chemotherapy treatment of the cell free DNA (cfDNA) concentration and tumor burden, analysis the correlation between the changes and prognosis.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | Observation | observe the association of ctDNA with efficacy of treatment |
Timeline
- Start date
- 2022-01-01
- Primary completion
- 2025-12-31
- Completion
- 2026-12-31
- First posted
- 2021-10-04
- Last updated
- 2021-10-04
Source: ClinicalTrials.gov record NCT05066945. Inclusion in this directory is not an endorsement.