NCT05063929

Impacts of Fruit on the Gut Health and Human Health

An Investigation of the Impact of Fruit on the Gut Microbiota and Its Metabolites: Connections to Human Health

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: San Diego State University · Academic / Other
• Sex: All
• Age: 30 Years – 70 Years
• Healthy volunteers: Accepted

Summary

The objectives of this study are to investigate the effect of fruit consumption on the gut microbiota and their collective fecal and plasma metabolomes, vascular and cardiometabolic functions, cognition, and motor control.

Detailed description

The Investigators findings will provide data critical to the understanding of the effects of fruit intake on the gut microbiome and the capacity of the microbiota to biotransform nutrients contained within fruits as well as the subsequent impact on circulating status of those metabolites. Concurrently, health outcomes that may be linked to these changes including cognition, motor control, vascular function and cardiometabolic health risk markers will be assessed in healthy adults.

Conditions

• Cardiometabolic Health
• Healthy Aging
• Cognition

Interventions

Type	Name	Description
OTHER	Fruit (2 cup eq)	participants will receive 2 cup eq fruits
OTHER	Fruit restriction (1/2 cup eq)	participants will receive 1/2 cups eq fruits

Timeline

• Start date: 2021-08-15
• Primary completion: 2023-08-15
• Completion: 2024-12-31
• First posted: 2021-10-01
• Last updated: 2025-01-08

Locations

1 site across 1 country: United States