Clinical Trials Directory

Trials / Recruiting

RecruitingNCT05058781

Minipuberty in Infants Born With Potential Hypogonadism Hypogonadotrope

Evaluation of Minipuberty in Infants Born With a Variation in Sexual Development

Status
Recruiting
Phase
Study type
Observational
Enrollment
100 (estimated)
Sponsor
Centre Hospitalier Universitaire Vaudois · Academic / Other
Sex
All
Age
9 Months
Healthy volunteers
Accepted

Summary

Disorders of sex development (DSD) occur in 1/3000 births and are defined by variation in aspect of external genital organs, e.g. cryptorchidism, hypospadias and micropenis in male infants and clitoral hypertrophy in female infants. Genetic, hormonal and environmental factors are implicated in DSD. Infants with congenital hypogonadism hypogonadotrope (CHH) can present with DSD. Evaluation of hormonal profile during minipuberty could be of great help to better characterize the etiology of DSD and CHH in particular. Our main objective is to study hormonal profile during the minipuberty of infants born with DSD or born from parents with CHH compared to controls.

Conditions

Timeline

Start date
2017-01-01
Primary completion
2026-12-31
Completion
2030-12-31
First posted
2021-09-28
Last updated
2022-07-22

Locations

1 site across 1 country: Switzerland

Source: ClinicalTrials.gov record NCT05058781. Inclusion in this directory is not an endorsement.