Clinical Trials Directory

Trials / Unknown

UnknownNCT05058768

Omics Sequencing of Exosomes in Body Fluids of Patients With Acute Lung Injury

Exosomes in Urine, Blood, and Alveolar Lavage Fluid From Patients With Acute Respiratory Distress Syndrome (ADRS) Were Sequenced by Omics

Status
Unknown
Phase
Study type
Observational
Enrollment
180 (estimated)
Sponsor
Nanfang Hospital, Southern Medical University · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Accepted

Summary

The exosomes in the experimental group and the control group were sequenced to find the difference of the two groups, providing a basis for subsequent basic research.

Detailed description

This study is an observational study, mainly collected by infection, trauma, burns and other non cardiac causes without any related comprehensive character drug treatment of acute respiratory distress (ARDS) in patients with blood, urine or alveolar lavage fluid specimens, used to extract exosomes for omics sequencing, relevant histomorphic variations in exosomes of this disease were obtained, In addition, functional verification of genes or proteins with different changes will be carried out to provide clinical basis for subsequent basic research.

Conditions

Interventions

TypeNameDescription
DIAGNOSTIC_TESTThe lungs causes and extrapulmonary factorsAcute lung injury due to internal and external pulmonary causes can be used as intervention items in this study, and intervention items can be excluded according to inclusion criteria and exclusion criteria.

Timeline

Start date
2022-05-06
Primary completion
2023-05-07
Completion
2024-12-16
First posted
2021-09-28
Last updated
2022-05-10

Locations

1 site across 1 country: China

Source: ClinicalTrials.gov record NCT05058768. Inclusion in this directory is not an endorsement.