NCT05055843

Novel Synthetic T2W MR Imaging and Spin Parameter Mapping Techniques for Screening Prostate Cancer

Novel Synthetic T2W MR Imaging and Spin Parameter Mapping Techniques for Prostate Cancer Without an Endorectal Coil

• Status: Active Not Recruiting
• Phase: N/A
• Study type: Interventional
• Enrollment: 33 (actual)
• Sponsor: M.D. Anderson Cancer Center · Academic / Other
• Sex: Male
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

This clinical trial studies examines a 3D magnetic resonance imaging (MRI) compared to standard MRI imaging techniques in screening patients with prostate cancer. Diagnostic procedures, such as MRI, may help find and diagnose prostate cancer. Computer systems that allow doctors to create a 3-dimensional (3-D) picture of the tumor may help in planning.

Detailed description

PRIMARY OBJECTIVE: I. To determine whether the image quality of the novel 3-dimensional (3D) T2-weighted imaging (T2W) synthetic imaging technique without endorectal coil is comparable to the 2-dimensional (2D) T2W imaging technique without endorectal coil. SECONDARY OBJECTIVE: I. To evaluate the qualitative diagnostic quality of the T2W images provided by the novel 3D technique, as determined by subjective scoring by experienced readers. EXPLORATORY OBJECTIVE: I. To investigate the feasibility of novel 3D synthetic imaging and multi-spin parameter mapping technique of prostate for the detection of clinically significant prostate cancer (csPCa). OUTLINE: Patients undergo 3D MRI imaging over 15 minutes with standard of care MRI or at a separate time.

Conditions

• Prostate Adenocarcinoma
• Prostate Carcinoma

Interventions

Type	Name	Description
PROCEDURE	Magnetic Resonance Imaging	Undergo 3D MRI

Timeline

• Start date: 2021-08-10
• Primary completion: 2027-01-31
• Completion: 2027-01-31
• First posted: 2021-09-24
• Last updated: 2026-04-15

Locations

1 site across 1 country: United States