NCT05050435

Early Cardiac Extubation After Cardiac Surgery

Early Cardiac Extubation After Cardiac Surgery: a Retrospective Single-center Non-inferiority Trial

• Status: Unknown
• Phase: —
• Study type: Observational
• Enrollment: 500 (estimated)
• Sponsor: University of Liege · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The management of heart valve disease is constantly evolving over time. The minimally invasive approach (mini-thoracotomy and J-hemisternotomy) is one of the major surgical evolutions. It has many advantages including, among others, a reduction of postoperative pain and the preservation of sternal stability This evolution of the surgical technique towards a less invasive approach encouraged the investigators to adapt the anesthetic management accordingly. In particular, immediate postoperative extubation appeared feasible. The investigators would therefore like to test the hypothesis that immediate extuation is non-inferior to delayed extubation with regard to patient safety. The investigators also investigated whether immediate extubation could be beneficiel in terms of vasopressors requirement, risk of early postoperative complications, fluid balance and length of stay in the intesive care unit and in the hopsital.

Conditions

• Post-operative Cardiac Surgery

Interventions

Type	Name	Description
PROCEDURE	Early extubation	Patients of the 2 groups are extubated at different moments: either immediately postoperatively, in the operating room, or after a few hours monitoring in ICU

Timeline

• Start date: 2021-08-30
• Primary completion: 2021-12-31
• Completion: 2021-12-31
• First posted: 2021-09-20
• Last updated: 2021-10-14

Locations

1 site across 1 country: Belgium