NCT05046054

The Effect of Transcutaneous Electrical Nerve Stimulation on Pain During Propofol Injection

• Status: Unknown
• Phase: N/A
• Study type: Interventional
• Enrollment: 80 (estimated)
• Sponsor: Kyungpook National University Hospital · Academic / Other
• Sex: All
• Age: 19 Years – 70 Years
• Healthy volunteers: Not accepted

Summary

Propofol, an intravenous sedative agent, frequently produces pain during injection. This study was designed to investigate whether transcutaneous electrical nerve stimulation could reduce pain during propofol injection. in minimizing propofol injection pain.

Detailed description

Twenty min after transcutaneous electrical nerve stimulation, the electrodes were removed and propofol 0.5 mg/kg was administered at the rate of 0.5 ml/sec using syringe pump. Propofol injection pain was evaluated by a study blinded anesthesiologist using a four point scale: 0=no (negative response to questioning), 1=mild pain (pain reported only in response to questioning without any behavioral sings), 2=moderate pain (pain reported in response to questioning and accompanied by a behavioral signs or pain reported spontaneously without questioning, 3=severe pain (strong vocal response or response accompanied by facial grimacing, arm withdrawal or tears).

Conditions

• Transcutaneous Electrical Nerve Stimulation
• Pain
• Propofol Adverse Reaction

Interventions

Type	Name	Description
DEVICE	transcutaneous electrical nerve stimulation	transcutaneous electrical nerve stimulation group received transcutaneous electrical nerve stimulation via two electrodes on the venous cannulation site 20 min before propofol injection
DEVICE	Placebo transcutaneous electrical nerve stimulation	Placebo transcutaneous electrical nerve stimulation group received no transcutaneous electrical nerve stimulation via two electrodes on the venous cannulation site 20 min before propofol injection

Timeline

• Start date: 2021-06-01
• Primary completion: 2022-01-30
• Completion: 2022-01-30
• First posted: 2021-09-16
• Last updated: 2022-01-19

Locations

1 site across 1 country: South Korea