NCT05041985

Clinical Efficacy of Diazepam After Whiplash

• Status: Completed
• Phase: Phase 4
• Study type: Interventional
• Enrollment: 89 (actual)
• Sponsor: Edin Mešanović · Academic / Other
• Sex: All
• Age: 18 Years – 70 Years
• Healthy volunteers: Accepted

Summary

Whiplash injury is very common and lot of patients which suffered the injury have chronic symptoms despite different treatment options. One of main symptoms include muscle spasm and pain caused by neck movement. Diazepam is a well known drug which can be used to treat muscle spasms. The aim of this study is to determine whether short term Diazepam therapy can have positive effect on long term outcomes after whiplash injury.

Detailed description

This randomized, assessor-blinded study was conducted on patients presented due to a cervical spine injury caused by a traffic accident in the previous 48 hours from 1st January 2020 to 31st December 2020. All the patient which were included in this study were divided into 2 groups: group A, the Test group, and group B, the control group. All patients signed the consent to participate in the study prior to randomization. During the initial examination a detailed history was taken and it included Visual Analog Pain Scale (VAS). On follow up examinations 7 days, 6 weeks and 6 months after the injury, all patients completed Neck disability index (NDI), Whiplash disability questionnaire (WDQ) as well as Visual Analog Pain Scale (VAS). Any patient which didn't complete all the follow up examination was excluded from the study.

Conditions

• Whiplash Injuries
• Whiplash Injury of Cervical Spine

Interventions

Type	Name	Description
DRUG	Diazepam Tablets	Diazepam 5 mg tablet once per day (bedtime) for 7 days

Timeline

• Start date: 2020-01-01
• Primary completion: 2020-12-31
• Completion: 2020-12-31
• First posted: 2021-09-13
• Last updated: 2024-12-04

Locations

1 site across 1 country: Bosnia and Herzegovina