NCT05041829

Dietary Sodium Intake and Blood Pressure in Living Kidney Donors

Dietary Sodium Intake and Blood Pressure in Living Kidney Donors: A Pilot Single-Center Crossover Single-Blind Randomized Controlled Trial

• Status: Suspended
• Phase: N/A
• Study type: Interventional
• Enrollment: 24 (estimated)
• Sponsor: University of California, Irvine · Academic / Other
• Sex: All
• Age: 18 Years
• Healthy volunteers: Accepted

Summary

This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake is superior to high dietary sodium intake in controlling blood pressure to be within the normotensive range in living kidney donors.

Detailed description

This is a pilot study to determine the feasibility of the study design and examine the main outcome whether low dietary sodium intake \<2.3 g/day (\<100 mmol/day) is superior to high dietary sodium intake ≥4 - \<6 g/day (≥174 - \<261 mmo/day) in controlling blood pressure (BP) to be within normotensive range, lowering systolic and diastolic blood pressures (SBP and DBP) from the baseline blood pressures, and decreasing the risk of hypertension, worsening kidney function, and proteinuria in living kidney donors between 5 and 12 months after living kidney donation?.

Conditions

• Hypertension
• Living Kidney Donor
• Dietary Sodium Intake

Interventions

Type	Name	Description
OTHER	Dietary sodium	Low sodium diet with sodium of \<2.3 g/day (\<100 mmol/day) and high sodium diet with sodium of ≥4 - \<6 g/day (≥174 - \<261 mmo/day)

Timeline

• Start date: 2021-11-03
• Primary completion: 2027-06-30
• Completion: 2028-06-30
• First posted: 2021-09-13
• Last updated: 2025-08-21

Locations

1 site across 1 country: United States