Trials / Completed
CompletedNCT05040256
Neurologic and Immunologic Characteristics of CTLA-4 and LRBA Hereditary Deficiency
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 20 (actual)
- Sponsor
- University Hospital, Montpellier · Academic / Other
- Sex
- All
- Age
- 12 Years
- Healthy volunteers
- Not accepted
Summary
CTLA4 and LRBA deficiencies are rare genetic disorders, recently described, and associated with multiple clinical features. It ranges from recurrent infections, auto-immunity, and organ infiltration with lymphocytes. Neurologic syndroms are described in up to 30% of patients, yet they are poorly defined to date. Early recognition of a specific pattern can be important, given that there is a targeted therapy in this situation.
Conditions
Timeline
- Start date
- 2021-02-01
- Primary completion
- 2021-08-01
- Completion
- 2021-09-30
- First posted
- 2021-09-10
- Last updated
- 2021-11-15
Locations
1 site across 1 country: France
Source: ClinicalTrials.gov record NCT05040256. Inclusion in this directory is not an endorsement.