Trials / Recruiting
RecruitingNCT05038553
Chronic Pain in Rheumatoid Arthritis
CNS Pain Mechanisms in Early Rheumatoid Arthritis: Implications for the Acute to Chronic Pain Transition
- Status
- Recruiting
- Phase
- —
- Study type
- Observational
- Enrollment
- 125 (estimated)
- Sponsor
- Northwestern University · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The objective is to identify modifiable clinical factors and neurobiological pathways that lead to the development of chronic pain in patients with early rheumatoid arthritis. Participants will undergo quantitative sensory testing, a type of testing that involves assessing response to well-defined, quantifiable painful stimuli, at 0, 3, and 12 months. A subset of participants will also undergo magnetic resonance imaging at 0 and 12 months to assess neuroimaging markers that have previously been shown to be involved in chronic pain.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| OTHER | No intervention | No intervention |
Timeline
- Start date
- 2021-10-12
- Primary completion
- 2026-04-30
- Completion
- 2026-04-30
- First posted
- 2021-09-09
- Last updated
- 2025-04-29
Locations
5 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05038553. Inclusion in this directory is not an endorsement.