Trials / Active Not Recruiting
Active Not RecruitingNCT05038124
A Study of Stereotactic Body Radiotherapy (SBRT) and Surgical Stabilization for People With Cancer That Has Spread to the Bone
A Pilot Study to Assess the Safety and Efficacy of Preoperative Stereotactic Body Radiotherapy for the Treatment of Metastatic Disease in Bone Requiring Surgical Stabilization
- Status
- Active Not Recruiting
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 39 (actual)
- Sponsor
- Memorial Sloan Kettering Cancer Center · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to test the safety of stereotactic body radiation therapy (SBRT) followed by surgical stabilization within 1 week. All participants will have metastatic cancer in the bone (bone metastases), and they will be at risk of pathologic fracture (broken bone caused by a disease). Another purpose of this study is to see if the treatment approach of SBRT followed by surgical stabilization within 1 week prevents cancer from returning to the bone.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| RADIATION | Preoperative Stereotactic Body Radiotherapy (SBRT) | Target lesions will be treated with preoperative SBRT consisting of biologically effective dose (BED10) of 50.4 - 81.6 Gy delivered in either three fractions or a single fraction. |
Timeline
- Start date
- 2021-06-30
- Primary completion
- 2027-06-01
- Completion
- 2027-06-01
- First posted
- 2021-09-08
- Last updated
- 2026-03-05
Locations
7 sites across 1 country: United States
Source: ClinicalTrials.gov record NCT05038124. Inclusion in this directory is not an endorsement.