NCT05037604

Factors Associated With Dermatoporosis

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 315 (actual)
• Sponsor: Universidad Autonoma de San Luis Potosí · Academic / Other
• Sex: All
• Age: 60 Years
• Healthy volunteers: Accepted

Summary

Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years. The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México. An observational, cross-sectional, descriptive, and analytical study was performed. Patients \>60 years old were selected. A clinical history, clinical examination, and application of a validated diagnostic self-questionnaire were performed.

Detailed description

Dermatoporosis is a chronic syndrome of skin insufficiency or fragility. It is characterized by cutaneous atrophy, senile purpura and stellate pseudoscars. Dermatoporosis prevalence is 37% in ≥65 years.The objective was to determine factors associated with this diagnosis in \>60 years old patients of the outpatient clinic in the Hospital Central "Dr. Ignacio Morones Prieto " San Luis Potosí, México. An observational, cross-sectional, descriptive and analytical study was performed. Through consecutive non-probabilistic sampling, patients \> 60 years old were selected, who underwent a clinical history, clinical examination, and the application of a validated diagnostic self-questionnaire. To determine the association of the factors, a multivariate logistic regression analysis, it will be used the PRIMERv6 software with the PERMANOVA package. A p \<0.05 was considered significant. The normality of the distribution of the continuous variables was evaluated with the Shapiro Wilk test. The Student's t test was performed on variables that met the homogeneity of variance requirements. In the variables that did not meet this criterion, a non-parametric analysis was performed with the Mann U Whitney test. For the analysis of categorical variables, Fisher's exact test or chi-square test was used. Continuous variables were reported by mean (median) \[Q1, Q3\] (min - max) and by standard deviations as their distribution corresponds. Nominal categorical variables were expressed as frequencies

Conditions

• Senile Purpura

Interventions

Type	Name	Description
OTHER	Questionnaire about associated factors	Questionnaire about age, prolonged sun exposure, intake of anticoagulants / antiplatelets, intake of oral steroids, chronic kidney disease. Maternal age\> 40 years in their last child , time of lactation per pregnancy and cumulative time of lactation. Age of the first pregnancy and age of menopause onset.
DIAGNOSTIC_TEST	Self questionnaire diagnostic tool	Self questionnaire of physical characteristics
OTHER	Physical Examination	Physical Examination made by a dermatologist

Timeline

• Start date: 2018-08-01
• Primary completion: 2018-11-30
• Completion: 2019-04-30
• First posted: 2021-09-08
• Last updated: 2021-09-08

Locations

1 site across 1 country: Mexico