NCT05034965

Dynamic Changes in Some Facial Muscles After Hyaluronic Acid Filler Injection

Dynamic Changes in Some Facial Muscles After Superficial Versus Deep Hyaluronic Acid Injection: An Electromyographic Study

• Status: Unknown
• Phase: EARLY_Phase 1
• Study type: Interventional
• Enrollment: 30 (estimated)
• Sponsor: Alexandria University · Academic / Other
• Sex: Female
• Age: 20 Years – 60 Years
• Healthy volunteers: Accepted

Summary

assess electrophysiological changes in some facial muscle dynamics following hyaluronic acid filler injection in superficial versus deep level of injection.

Detailed description

Participants will be subjected to injection of cross-linked hyaluronic acid fillers on both sides of the face in 3 different regions: temples, cheeks and chins. Each female will undergo: 1. Before injection: 1. Aesthetic facial clinical analysis. 2. Baseline quantitative surface electromyography. 3. Baseline digital photography. 2. Injection: Each female will receive the injection in the particular facial region at superficial level to the muscle (subcutaneous) on one side and the same amount at deep level to the muscle (supraperiosteal) on the other side. 3. One week after injection: 1. Follow up quantitative surface electromyography. 2. Follow up digital photography.

Conditions

• Changes in Facial Muscles Following Filler Injection

Interventions

Type	Name	Description
DRUG	hyaluronic acid filler injection	quantitative surface electromyography before injection(baseline) and one week after injection

Timeline

• Start date: 2021-10-01
• Primary completion: 2022-10-01
• Completion: 2022-10-01
• First posted: 2021-09-05
• Last updated: 2021-09-05

Locations

1 site across 1 country: Egypt