NCT05031286

Differences in Pain Processing Between Men and Women

Differences in Sensitization Between Men and Women After Cutaneous Thermal Stimuli

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 66 (actual)
• Sponsor: Balgrist University Hospital · Academic / Other
• Sex: All
• Age: 18 Years – 40 Years
• Healthy volunteers: Accepted

Summary

Many chronic pain conditions show clear differences between between men and women, such as reported pain intensities or treatment effects, with chronic pain conditions being generally more frequent in women. Yet, the underlying mechanisms causing these differences are poorly understood. Central sensitization (CS) is considered one important mechanism in pain patients which differs between female and male patients. The central hypothesis is that already in the healthy population CS processes are more pronounced in women than in men.

Conditions

• Central Sensitisation

Interventions

Type	Name	Description
OTHER	Cutaneous thermal stimuli	Application of thermal stimuli of different intensities to the skin

Timeline

• Start date: 2021-05-01
• Primary completion: 2022-12-31
• Completion: 2022-12-31
• First posted: 2021-09-01
• Last updated: 2023-04-11

Locations

1 site across 1 country: Switzerland