Trials / Completed
CompletedNCT05030376
Intraileal Glucose vs. Saline Infusion on Hormone Secretion and Glycemic Excursions
Comparative Effects of Intraileal Glucose vs. Saline Infusion on Hormone Secretion and Glycemic Excursions in Subjects With Ileostomy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 15 (actual)
- Sponsor
- Qilu Hospital of Shandong University · Academic / Other
- Sex
- All
- Age
- 18 Years – 75 Years
- Healthy volunteers
- Accepted
Summary
The distal ileum, where the glucagon-like peptide 1 (GLP-1) releasing cells predominate, is an important organ in mediating glycemic control. However, the distal ileum is not easy to access and the correspond in vivo research remains to be difficult. The investigators intend to recruit subjects who underwent rectal surgery with simultaneous protective ileostomy and evaluate hormone secretion and glycemic excursions via ileostomy glucose or saline infusion, and quantify the glucose absorption rate within the distal ileum.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DIETARY_SUPPLEMENT | intraileal infusion | intraileal glucose or intraileal saline infusion |
Timeline
- Start date
- 2021-09-22
- Primary completion
- 2022-03-01
- Completion
- 2022-03-01
- First posted
- 2021-09-01
- Last updated
- 2022-04-26
Locations
2 sites across 1 country: China
Source: ClinicalTrials.gov record NCT05030376. Inclusion in this directory is not an endorsement.