NCT05028764

Determine Range of Tissue Frataxin Concentrations and Other Potential Biomarkers

A Study to Determine the Range of Tissue Frataxin Concentrations and Other Potential Biomarkers for Friedreich's Ataxia in Normal Healthy Volunteers

• Status: Completed
• Phase: —
• Study type: Observational
• Enrollment: 60 (actual)
• Sponsor: Larimar Therapeutics, Inc. · Industry
• Sex: All
• Age: 18 Years – 50 Years
• Healthy volunteers: Accepted

Summary

To examine range of tissue frataxin (FXN) concentrations, specific ribonucleic acids, other proteins and specialized lipids in the buccal cells, blood, and skin cells of normal healthy volunteers without Friedreich's ataxia (FRDA).

Detailed description

Primary Objective: To examine the range of tissue frataxin (FXN) concentrations in the buccal cells, blood, and skin cells of normal healthy volunteers without FRDA. Secondary Objective: To examine the range of specific ribonucleic acids (RNAs), other proteins, and specialized lipids in the buccal cells, blood, and skin cells of normal healthy volunteers without FRDA.

Conditions

• Friedreich Ataxia
• Healthy Volunteers

Interventions

Type	Name	Description
DIAGNOSTIC_TEST	Buccal Swabs, Blood Draws and Skin Punch Biopsy	Buccal Swabs - FXN and specific RNA markers; Blood Draws - Lipid panel, Protein Marker Analysis and Gene RNA Analysis; Skin Punch Biopsy - Protein Markers

Timeline

• Start date: 2021-08-04
• Primary completion: 2022-02-04
• Completion: 2022-02-04
• First posted: 2021-08-31
• Last updated: 2022-02-24

Locations

1 site across 1 country: United States