NCT05026554

Characterization of Chronic Hand Eczema

Pathophysiological Characterization of Chronic Hand Eczema Subtypes and Atopic Dermatitis With Noninvasive Molecular and Imaging Techniques in Subjects With Moderate to Severe Chronic Hand Eczema, Subjects With Atopic Dermatitis, and Healthy Volunteers

• Status: Recruiting
• Phase: —
• Study type: Observational
• Enrollment: 270 (estimated)
• Sponsor: Dr. Robert Bissonnette · Academic / Other
• Sex: All
• Age: 18 Years – 65 Years
• Healthy volunteers: Accepted

Summary

Prospective longitudinal study to characterize Choronic Hand Eczema (CHE) subtypes and Atopic Dermatitis (AD) with noninvasive molecular and imaging techniques, and assess changes through time and its association with quality of life.

Detailed description

Prospective longitudinal study of adult patients with moderate to severe chronic hand eczema, subject with modreate to severe Atopic Dermatitis and healthy volenteers to assess changes in morphological parameters and molecular signatures with non-invasive techniques.In addition, disease severity and their association with occupation, smoking status, quality of life will be evaluated per CHE subtypes and compared to subjects with only AD. Samples and data collected from healthy volunteers will be used as controls in the analyses.

Conditions

• Chronic Hand Eczema
• Atopic Dermatitis

Interventions

Type	Name	Description
GENETIC	Tape stripping	Optional genetic analysis for chronic hand eczema

Timeline

• Start date: 2021-06-30
• Primary completion: 2027-06-30
• Completion: 2027-09-30
• First posted: 2021-08-30
• Last updated: 2026-04-09

Locations

1 site across 1 country: Canada