Trials / Completed
CompletedNCT05025228
Analgesic Effect of Paracetamol in Patients With Femur Fracture: is Intravenous Better Than Oral?
- Status
- Completed
- Phase
- —
- Study type
- Observational
- Enrollment
- 170 (actual)
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
The purpose of this study is to monitor severe pain for femur fracture after treatment with paracetamol IV or OR.
Detailed description
The investigators enrolled 170 consecutive patients with femur fracture and severe pain. The patients received an initial analgesic treatment with paracetamol orally (OR) or intravenously (IV). The primary outcome was the reduction of pain of 1 point at visual analogue scale for pain (VAS) after the 1 st hour of treatment (T1). Secondary endpoints included the reduction of pain of at least 2 points on the VAS scale at the 4 th hour (T4), the need of rescue therapy and the number of adverse events.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| DRUG | Paracetamol | Paracetamol given orally or intravenously |
Timeline
- Start date
- 2019-06-01
- Primary completion
- 2020-06-30
- Completion
- 2020-06-30
- First posted
- 2021-08-27
- Last updated
- 2021-10-11
Locations
1 site across 1 country: Italy
Source: ClinicalTrials.gov record NCT05025228. Inclusion in this directory is not an endorsement.