NCT05022823

Exercise and Compression for Lymphedema

Decongestive Progressive Resistance Exercise With Advanced Compression for Breast Cancer Related Lymphedema Management (DREAM): A Randomized Control Trial

• Status: Completed
• Phase: N/A
• Study type: Interventional
• Enrollment: 40 (actual)
• Sponsor: AHS Cancer Control Alberta · Academic / Other
• Sex: Female
• Age: 18 Years
• Healthy volunteers: Not accepted

Summary

The purpose of this study is to investigate the benefit of combining resistance exercise with use of a compression sleeve on arm lymphedema. In the study, participants will be taught a resistance exercise that follows the decongestive exercise sequence. This program is called "decongestive progressive resistance exercise" (DPRE). To evaluate the benefit from use of a compression garment on the arm. Some participants will wear their usual compression sleeve during exercise and others will use an adjustable compression wrap. The investigators hope to see if this type of combined program is helpful for women with lymphedema. The investigators also want to see if there are benefits from the addition of use of an adjustable compression wrap during exercise over use of a regularly prescribed compression sleeve.

Conditions

• Breast Cancer Related Lymphedema

Interventions

Type	Name	Description
DEVICE	Compression sleeve, worn during exercise	Participants wear their daytime compression sleeve during the DPRE program.
DEVICE	Adjustable Compression (AC) garment, worn during exercise	Participants wear an Adjustable Compression (AC) garment during the DPRE program. Participants will be fitted for an Adjustable Compression garment and instructed in its application by a physical therapist.
DEVICE	Compression sleeve, daytime wear	Compression sleeve worn for at least 12 hours per day, seven days a week.
BEHAVIORAL	Decongestive Progressive Resistance Exercise program	Supervised DPRE exercise program, twice a week for 12 weeks. Exercises will be individualized and offered in a group-based format. After the 12-week intervention, participants will continue the same program (independently) twice weekly for an additional 12 weeks at home or in a community-based fitness center or attend supervised group exercise sessions virtually.
BEHAVIORAL	Home exercise program	Participants are provided with a home exercise program that follows the decongestive exercise sequence and instructed to perform the exercise sequence once daily for a 10-15 minute period.

Timeline

• Start date: 2022-06-29
• Primary completion: 2024-02-08
• Completion: 2024-02-08
• First posted: 2021-08-26
• Last updated: 2025-06-27

Locations

1 site across 1 country: Canada