Trials / Completed
CompletedNCT05020795
Effect of Proximal Blood Flow Arrest During Endovascular Thrombectomy
- Status
- Completed
- Phase
- N/A
- Study type
- Interventional
- Enrollment
- 134 (actual)
- Sponsor
- Nottingham University Hospitals NHS Trust · Academic / Other
- Sex
- All
- Age
- 18 Years
- Healthy volunteers
- Not accepted
Summary
Endovascular thrombectomy (EVT) has become the standard of care for large vessel occlusion in acute ischaemic stroke (AIS). During clot-retrieval, simultaneous balloon inflation within the internal carotid artery offers transient proximal blood flow arrest, potentially preventing distal clot migration or embolisation to new vascular territories. Retrospective studies indicate that this may improve complete vessel recanalisation rates and may translate to improved functional independence. However, lack of high-quality evidence demonstrating the efficacy of simultaneous balloon inflation has led to clinical equipoise with heterogeneity of practice globally.
Conditions
Interventions
| Type | Name | Description |
|---|---|---|
| PROCEDURE | Endovascular thrombectomy | Clot retrieval for large vessel occlusion in acute ischaemic stroke |
Timeline
- Start date
- 2021-10-07
- Primary completion
- 2023-10-01
- Completion
- 2023-11-01
- First posted
- 2021-08-25
- Last updated
- 2025-06-27
Locations
1 site across 1 country: United Kingdom
Source: ClinicalTrials.gov record NCT05020795. Inclusion in this directory is not an endorsement.