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UnknownNCT05019300

Long-term Neurocognitive and Psychiatric Consequences in Severe COVID-19 Survivors.

Long-term Neurocognitive and Psychiatric Consequences of COVID-19 in Patients Discharged From Critical Care Units. A Cohort Study of the Advance Interdisciplinary Rehabilitation Register (AIRR) Covid-19 Working Group.

Status
Unknown
Phase
Study type
Observational
Enrollment
80 (estimated)
Sponsor
Pontificia Universidad Catolica de Chile · Academic / Other
Sex
All
Age
18 Years
Healthy volunteers
Not accepted

Summary

Long-term neurocognitive and psychiatric consequences of COVID-19 remain mostly unknown to date. It has been reported that coronaviruses cause direct central nervous system infection (Needham et al. 2020). Besides that, new or worsening cognitive impairment commonly occurs and persists in survivors of intensive care unit (ICU) stay (Hosey \& Needham. 2020). The purpose of our study is to search and describe the cognitive and psychiatric long-term consequences of COVID-19 on patients who have been discharged from critical care units. This is an ambidirectional cohort study, that attempts to follow adults discharged from critical Care Units Adults due to COVID-19 up to 12 months after discharge, to evaluate the presence of cognitive impairment, linguistic and phonation function, depression, fatigue, functional gastroenterological symptoms, anxiety, or post traumatic disorder, and performance in activities of daily living and physical response to exercise as well.

Conditions

Interventions

TypeNameDescription
BIOLOGICALExposure: COVID-19 severityCOVID-19 severity between 4 to 7 points according the seven-category scale of clinical status reported by Huang et al. (2021) and severe to critical symptomatic levels on spectrum of disease reported by Wu and McGoogan (2020).

Timeline

Start date
2021-05-24
Primary completion
2021-09-01
Completion
2021-10-01
First posted
2021-08-24
Last updated
2021-08-31

Locations

1 site across 1 country: Chile

Source: ClinicalTrials.gov record NCT05019300. Inclusion in this directory is not an endorsement.